Manuscripts

Manuscript Pharmacy Dispensing Journal – Hobart 1929-1931

Large cloth backed ledger recording the precise details of prescriptions diligently recorded against each patients name and cross referenced to a list of individuals at the front. 502 pages of prescriptions and the many receivers listed in an alphabetical construction as the front. Nice condition- entries in a strong legible hand.

42cm tall by 18cm and 5cm thick a fair weight so not suitable for Overseas. Red leather title label.. some scribbled names which do not seem to correlate with the J.R.R. and M.B and A.E.G. of the dispensing chemists.

The date range 1929 etc is right on the bell for the discovering of penicillin … antibiotics in the broader structure coming much later. So here we still have a host of syrups and powders and the Elixir Simplex … and chloroform (for personal use?) and a grand mixture of lead and opioid products.

Interesting Pharmaceutical Record approaching 100 years.

$170.00

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Nugae Canorae Medicae – Sir Andrew Douglas Maclagan – First edition 1850 – With Additional Contemporary Manuscript Content

Translates literally “Silly Medical Songs” and they are. Andrew Douglas Maclagan (1812-1900) was an eminent Scottish surgeon and toxicologist. In his lifetime he was President of five of the mots distinguished Societies in Scotland. As a toxicologist he was called to Court to give evidence … as a young man he supported the prosecution in the Burke and Hare affair.

Printed by Thomas Constable, Edinburgh in 1850 – a first edition (it was reprinted in 1873). Effectively self published. Maclagan vaguely covered his identity as the author is names as “The Poet Laureate of the New Town Dispensary”. Octavo, bark brown embossed cloth covered boards with gilt titling to front, 82 pages with manuscript additions to rear end paper. Remnant seal to back paste down.

Given the period any reader will be pleasantly surprised how amusing the said poem/songs are … and much fun must have been had with them. Footnotes have been provided which explain the circumstances and sometimes individuals at fault or lampooned. No punches held.

What makes this copy more charming is the manuscript addition. Internally they sometimes correct the events suggested. At the rear we have in neat manuscript further ditties by Maclagan that are not in the published work. Clearly someone who knew the great man very well. 19thC press clipping re Maclagan affixed front free end.

Silly Songs by a most distinguished physician.

$180.00

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Exchange of Letters between Sir Leslie Orme Wilson and the Maharaja of Gondal on the former’s appointment as the Governor of Bombay – 1923. Subsequently Wilson to become Governor of Queensland

An official exchange along with a corrected draft from the Maharaja so clearly from the files of his office.

Military man and parliamentarian Leslie Orme Wilson (1876- 1955) was appointed Governor of Bombay (1923-1926). His formal advice to His Highness Sir Bhagwatsinhji Sagramji – Thakor Saheb of Gondal ((1865-1944) was sent dated 13 December 1923 on the rather striking elaborately bordered paper of the day and regime. It is framed with a “Friendly disposition”.

The delightful response was not made until 5th February the following year and I have no doubt there may have been an underlying message despite the responses carefully crafted words “great pleasure to receive the assurance of the friendly disposition”. We also like the fact that the Maharaja’s similarly elaborate paper has retained far more gold over the years than his British counterpart.

There relationship did in indeed prove friendly and Wilson was “sent on” to Brisbane to become it’s longest serving Governor from 1932 through the war years to 1946. He was the head honcho in the Queensland masons and did a lot of tress planting including sone of the nice ones down around the beginning of Coronation drive – have they survived the continuous development?

An unusual and friendly piece of history with a Queensland connection

$80.00

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Letter from (Sir) Francis Chichester – 1931

What at first seems a rather innocuous letter from Francis (later Sir Francis) Chichester on proper investigation is rather interesting.

Long before Chichester became the solo around the world yachtsman, we all know him for he was a pioneering aviator. He learned to fly in 1929 and bought a de Havilland Gypsy Moth (hence the later name of his famous yacht). He attempted to beat Bert Hinkler’s record England to Australia, but the plane malfunctioned. Being a “born to win” sort of man he decided on the first Trans Tasman flight NZ to Australia which he accomplished in 1931. During which he was the first to land an aeroplane at Lord Howe Island and Norfolk Island.

Back to the letter and we see that he was staying at The Australia Hotel Sydney and that the letter is prepared dated 193x. We are confident that this places Chichester in his hotel digs just after the historic event. The addressee Mr Crome is undoubtedly Ernest Alfred Crome who was or certainly became, along with his wife, the greatest collector of aviator memorabilia in Australia. Whilst the items sent by Chichester are a little difficult to understand they are likely conjured up ephemera that relate to that great aviation event.

Crome gave his massive collection to the Sydney Museum and worked there for five of his final years helping them assimilate and augment the collection.

Brief but poignant letter from a great aviator to a great aviation admirer – Chichester to Australian Ernest Crome

$60.00

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Australian Born Nobel Prize Winner in Chemistry – [Sir] John Warcup Cornforth – Signed manuscript letter

A very special letter (dated 1980) not only because of its truly distinguished author but here we have real content. Letters by Nobel Prize winners are not terribly rare but so often are perfunctory, relating to meetings, events or simply lunch. Here we have real, in depth, chemistry. The receiver, Dr Buckel, a distinguished scientist in his own right, may have been rather embarrassed on receipt. Cornforth believes that Buckel had tackled his work from completely the wrong route … indeed Cornforth is puzzled and goes on to set out in great detail his preferred option(s). In our view the content reveals the manner in which Cornforth visualises the solution to the problem from first principles then more complex mechanisms and solutions and alternative options as his thinking develops. The fact of his genius is plain in the writing. We love it.

The only Australian to date to have won the Nobel Prize for Chemistry.

Dear Dr Buckel

Thank you for your letter of 7 October. I was interested by your account of the work with glutaconate, but rather puzzled that you did not try the degradation to malate in the way you say I suggested. I have forgotten the details of our conversation during your very welcome visit, but certainly I would expect direct oxidation of glutaconate to malate by permanganate to be most unfavourable. This is because in glutaconate one has the combination of a double bond deactivated by conjunction with a carboxyl and a strongly activated methylene group. In these circumstances one would expect permanganate to attack the methylene group to a considerable and perhaps predominant extent, before the double bond was attacked. This is why it would be preferable to use a specific agent first to hydroxylate the double bond. Indeed, it should be possible to proceed in high yield to malic acid by making use of the fact that one of the hydroxyl groups will form a lactone. Thus: … chemical formulae.

He goes on …

The opening of the lactone ring is generally faster than the hydrolysis of an ester group (especially a benzoate) so that if you put the acetyl or benzoyl-lactone in hot water and neutralized the acidity as it appeared you should be able to get a clean ring-opening without other chemical changes. I really think you should try this – it seems so much simpler than the routes you have explored.

I will ask at Sittingbourne if they have any chiral acetate left – I brought none of it here. It will be ten years old now and will have lost nearly half its original radioactivity but a specimen tested for chirality about five years ago seemed not to have been racemized by radiolysis or by preservation in the form of aqueous potassium acetate. However, I wonder if this is the best way to make chiral 4-substituted glutamates and I wonder if you could do this from chirally tritiated malate using R-citrate synthetase and malate dehydrogenase, following this by treatment of the citrate with aconitase, isocitrate dehydrogenase etc. This should give you a totally chiral product whereas by starting from acetate you are at the mercy of isotope effects.

Cornforth goes on to offer his help in finding candidates for research, a task he may achieve on Thursday at The Royal Society where he is attending a discussion on glycolytic enzymes. There it is again proof The Royal Society …is the best Club in the World!

Sydney born Cornforth was totally deaf by the age of twenty but already recognised as and exceptional academic. He went to England, Oxford, along with a similarly gifted chemist Rita Harradence, who he later married. His relationship with Rita started over a broken Claisen flask .. Cornforth was a expert glassblower … something that was essential in the aspiring chemist in the 1930’s. Interestingly, there was no place in Australia where one could do a decent PhD in chemistry at that time. Naturally at Oxford Cornforth was in his element. He went on to be the first to synthesise cholesterol and had a hand in stabilising penicillin building on the work of fellow Australian Howard Florey. Cornforth was awarded the Nobel Prize in 1975 and coincidental with being made “Australian of the Year”. Cornforth also won the Davy Medal, Copley Medal, was Knighted and made Fellow of the Royal Society

Scientific gold – Manuscript letter with considerable scientific content by Australian Nobel Prize winner John Warcup Cornforth

$590.00

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Edward Elgar Symphony No 2 – with Expert Manuscript Annotations

Published by music score specialists Novello of Sevenoaks, Kent. No date originally published in 1911 and dedicated to the memory of the then late king Edward VII.

Written, or designed as Elgar would have it, in 1910 as a tribute that missed publication before the King’s passing.

Soft cover 171 pages of score Symphony No 2 in E Flat Op 63, copyright by the publisher. Printed in a facsimile style of the original. Carried the name at front John Snowdon, probably the musical talent who lives in the Huon area.

What makes this special in our view, apart from the magnificence of the piece, is the manuscript interpretive annotations, mainly towards the front of the work … robust theme; E Flat with colouring; rising 5th syncopation; similar to Brahms; wild outbursts of orchestral virtuosity; ghost episode … we love it.

Elgar’s magnificent No 2 with expert annotations.

$25.00

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Manuscript Pharmacy Dispensing Journal – Hobart 1929-1931

Nugae Canorae Medicae – Sir Andrew Douglas Maclagan – First edition 1850 – With Additional Contemporary Manuscript Content

Exchange of Letters between Sir Leslie Orme Wilson and the Maharaja of Gondal on the former’s appointment as the Governor of Bombay – 1923. Subsequently Wilson to become Governor of Queensland

Letter from (Sir) Francis Chichester – 1931

Australian Born Nobel Prize Winner in Chemistry – [Sir] John Warcup Cornforth – Signed manuscript letter

Edward Elgar Symphony No 2 – with Expert Manuscript Annotations

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